Observation of Pulsatile Hormones
Saliva is a biological specimen that is easy to obtain at regular intervals, i.e. multiple times in one day, allowing for observation of pulsating hormones, or hormones that should rise or fall during the 24 hour day night cycle. For this simple reason, the use of saliva for testing hormones has rapidly gained in popularity for diagnostic investigations by medical practitioners but also for use in the home.
We measure the unbound hormone component using Saliva
The endocrine organs (for example the adrenal gland) produce and secrete hormones into the blood stream that travel around the body to their site of action (for example the ovaries). In the blood however, the hormones are mostly bound to binding proteins which prevent the hormone from activating its receptor at the target tissue. So when a hormone is attached to its binding protein it is biologically inactive.
How accurate is hormone saliva testing?
Very! Aside from the practical aspects of using saliva for steroid hormone testing, the tests are widely accepted in the medical profession to provide an accurate and reliable measure of hormone levels at the times of collection. A saliva test measures free hormone and its multi-point versatility makes it a valuable tool for evaluating hormone status.
Once the saliva specimens arrive at the laboratory, they undergo rigorous testing that is both sensitive and highly specific to the hormone being tested. Advanced Tandem-MS testing can detect very low levels of a given hormone and employs antibody binding methods that lead to only the specific hormone of interest being measured (avoiding false positives). The laboratory applies strict quality control checks ensuring that their test results are high quality and accurate.
Established Ranges of Hormone Levels Comparison
The popularity of saliva hormone testing has led to the establishment of well-defined hormone reference ranges in healthy individuals, meaning that hormone results can be compared against the most relevant typical range. Factors such as sex, age, history and menopausal status all affect normal hormone ranges, and can be adjusted for, providing an accurate assessment of hormone profile relative to expected norms.
Saliva Testing for Hormones – Accuracy over Haste
How long testing takes depends on the laboratory, the equipment they use, and also the volume of hormones being tested. Laboratories who run low total volume of tests may run a single batch for a particular hormone once per week, where as larger, busier laboratories may do them daily. In the case of TestoChecker and its selected laboratory, testing turnaround time is very quick. Test wait time using TestoChecker hormone test kits is between 5 – 11 working days. For a more specific breakdown of individual hormone test wait times Go Here.